An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunotherapy for the treatment of cutaneous melanoma: version 2.0.

{"article_title":"An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunotherapy for the treatment of cutaneous melanoma: version 2.0.","author":"Sullivan RJ, Atkins MB, Kirkwood JM, Agarwala SS, Clark JI, Ernstoff MS, Fecher L, Gajewski TF, Gastman B, Lawson DH, Lutzky J, McDermott DF, Margolin KA, Mehnert JM, Pavlick AC, Richards JM, Rubin KM, Sharfman W, Silverstein S, Slingluff CL Jr, Sondak VK, Tarhini AA, Thompson JA, Urba WJ, White RL, Whitman ED, Hodi FS, Kaufman HL","journal_title":"Journal for immunotherapy of cancer","issn":"2051-1426","isbn":"","publication_date":"2018-05-30","volume":"6","issue":"1","first_page":"44","page_count":"","accession_number":"29848375","doi":"10.1186\/s40425-018-0362-6","publisher":"BMJ Publishing Group Ltd","doctype":"Journal Article","subjects":"Antineoplastic Agents, Immunological therapeutic use; Melanoma drug therapy; Skin Neoplasms drug therapy; Consensus; Humans; Immunotherapy; Melanoma pathology; Neoplasm Staging; Skin Neoplasms pathology","interest_area":["Oncology"," Dermatology"],"abstract":"Background: Cancer immunotherapy has been firmly established as a standard of care for patients with advanced and metastatic melanoma. Therapeutic outcomes in clinical trials have resulted in the approval of 11 new drugs and\/or combination regimens for patients with melanoma. However, prospective data to support evidence-based clinical decisions with respect to the optimal schedule and sequencing of immunotherapy and targeted agents, how best to manage emerging toxicities and when to stop treatment are not yet available. Methods: To address this knowledge gap, the Society for Immunotherapy of Cancer (SITC) Melanoma Task Force developed a process for consensus recommendations for physicians treating patients with melanoma integrating evidence-based data, where available, with best expert consensus opinion. The initial consensus statement was published in 2013, and version 2.0 of this report is an update based on a recent meeting of the Task Force and extensive subsequent discussions on new agents, contemporary peer-reviewed literature and emerging clinical data. The Academy of Medicine (formerly Institute of Medicine) clinical practice guidelines were used as a basis for consensus development with an updated literature search for important studies published between 1992 and 2017 and supplemented, as appropriate, by recommendations from Task Force participants. Results: The Task Force considered patients with stage II-IV melanoma and here provide consensus recommendations for how they would incorporate the many immunotherapy options into clinical pathways for patients with cutaneous melanoma. Conclusion: These clinical guidleines provide physicians and healthcare providers with consensus recommendations for managing melanoma patients electing treatment with tumor immunotherapy.","url":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&db=mdl&AN=29848375","isPdfLink":false,"isSAML":true,"an":"29848375","number_other":"","type_pub":"","issn_electronic":"2051-1426","languages":"English","language":"eng","date_entry":"Date Created: 20180601 Date Completed: 20200131 Latest Revision: 20231112","date_update":"20240105","titleSource":"Journal for immunotherapy of cancer [J Immunother Cancer] 2018 May 30; Vol. 6 (1), pp. 44. Date of Electronic Publication: 2018 May 30.","date_pub_cy":"","type_document":"","contract_publisher":"","authored_on":"2018-05-30","description":"Background: Cancer immunotherapy has been firmly established as a standard of care for patients with advanced and metastatic melanoma. Therapeutic outcomes in clinical trials have resulted in the approval of 11 new drugs and\/or combination regimens for patients with melanoma. However, prospective data to support evidence-based clinical decisions with respect to the optimal schedule and sequencing of immunotherapy and targeted agents, how best to manage emerging toxicities and when to stop treatment are not yet available.<br \/>Methods: To address this knowledge gap, the Society for Immunotherapy of Cancer (SITC) Melanoma Task Force developed a process for consensus recommendations for physicians treating patients with melanoma integrating evidence-based data, where available, with best expert consensus opinion. The initial consensus statement was published in 2013, and version 2.0 of this report is an update based on a recent meeting of the Task Force and extensive subsequent discussions on new agents, contemporary peer-reviewed literature and emerging clinical data. The Academy of Medicine (formerly Institute of Medicine) clinical practice guidelines were used as a basis for consensus development with an updated literature search for important studies published between 1992 and 2017 and supplemented, as appropriate, by recommendations from Task Force participants.<br \/>Results: The Task Force considered patients with stage II-IV melanoma and here provide consensus recommendations for how they would incorporate the many immunotherapy options into clinical pathways for patients with cutaneous melanoma.<br \/>Conclusion: These clinical guidleines provide physicians and healthcare providers with consensus recommendations for managing melanoma patients electing treatment with tumor immunotherapy.","upload_link":"https:\/\/dx.doi.org\/doi:10.1186\/s40425-018-0362-6","no_of_pages":"","authored_by":"Sullivan RJ, Atkins MB, Kirkwood JM, Agarwala SS, Clark JI, Ernstoff MS, Fecher L, Gajewski TF, Gastman B, Lawson DH, Lutzky J, McDermott DF, Margolin KA, Mehnert JM, Pavlick AC, Richards JM, Rubin KM, Sharfman W, Silverstein S, Slingluff CL Jr, Sondak VK, Tarhini AA, Thompson JA, Urba WJ, White RL, Whitman ED, Hodi FS, Kaufman HL","additionalInfo":{"Authored_By":"Sullivan RJ, Atkins MB, Kirkwood JM, Agarwala SS, Clark JI, Ernstoff MS, Fecher L, Gajewski TF, Gastman B, Lawson DH, Lutzky J, McDermott DF, Margolin KA, Mehnert JM, Pavlick AC, Richards JM, Rubin KM, Sharfman W, Silverstein S, Slingluff CL Jr, Sondak VK, Tarhini AA, Thompson JA, Urba WJ, White RL, Whitman ED, Hodi FS, Kaufman HL","Journal_Info":"Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE","Publication_Type":"Journal Article; Practice Guideline","Published_Date":"2018-05-30","Source":"Journal for immunotherapy of cancer [J Immunother Cancer] 2018 May 30; Vol. 6 (1), pp. 44. Date of Electronic Publication: 2018 May 30.","Languages":"English","Electronic_ISSN":"2051-1426","MeSH_Terms":"Antineoplastic Agents, Immunological\/*therapeutic use , Melanoma\/*drug therapy , Skin Neoplasms\/*drug therapy, Consensus ; Humans ; Immunotherapy ; Melanoma\/pathology ; Neoplasm Staging ; Skin Neoplasms\/pathology","Subjects":"Consensus, Humans, Immunotherapy, Melanoma pathology, Neoplasm Staging, Skin Neoplasms pathology, Antineoplastic Agents, Immunological therapeutic use, Melanoma drug therapy, Skin Neoplasms drug therapy","Title_Abbreviations":"Journal for immunotherapy of cancer","Volume":"6"},"header":{"DbId":"mdl","DbLabel":"MEDLINE Ultimate","An":"29848375","RelevancyScore":"749","PubType":"Academic Journal","PubTypeId":"academicJournal","PreciseRelevancyScore":"749.387817382813"},"plink":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=29848375&authtype=shib&custid=ns346513&group=main&profile=eds"}