SEOM clinical guidelines for diagnosis and treatment of glioblastoma (2017).

{"article_title":"SEOM clinical guidelines for diagnosis and treatment of glioblastoma (2017).","author":"Mart\u00ednez-Garcia M, \u00c1lvarez-Linera J, Carrato C, Ley L, Luque R, Maldonado X, Mart\u00ednez-Aguillo M, Navarro LM, Vaz-Salgado MA, Gil-Gil M","journal_title":"Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico","issn":"1699-3055","isbn":"","publication_date":"2018-01-01","volume":"20","issue":"1","first_page":"22","page_count":"","accession_number":"29086250","doi":"","publisher":"Springer","doctype":"Journal Article","subjects":"Brain Neoplasms diagnosis; Brain Neoplasms therapy; Glioma diagnosis; Glioma therapy; Humans","interest_area":["Neurology"," Oncology"],"abstract":"Glioblastoma (GB) is the most common brain malignancy and accounts for over 50% of all high-grade gliomas. Radiotherapy (RT) with concomitant and adjuvant temozolomide (TMZ) chemotherapy is the current standard of care for patients with newly diagnosed GB up to age 70. Recently, a new standard of care has been adopted for elderly patients (\u2265 65 years) based on short course of RT and TMZ. Several clinically relevant molecular markers that assist in diagnosis and prognosis have recently been identified. The treatment for recurrent GB is not well defined, and decision-making is usually based on prior strategies as well as several clinical and radiological factors. The presence of neurologic deficits and seizures can significantly impact quality of life.","url":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&db=mdl&AN=29086250","isPdfLink":true,"isSAML":false,"an":"29086250","number_other":"","type_pub":"","issn_electronic":"1699-3055","languages":"English","language":"eng","date_entry":"","date_update":"","titleSource":"Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2018 Jan; Vol. 20 (1), pp. 22-28. Date of Electronic Publication: 2017 Oct 30.","date_pub_cy":"","type_document":"","contract_publisher":"","authored_on":"2018-01-01","description":"Glioblastoma (GB) is the most common brain malignancy and accounts for over 50% of all high-grade gliomas. Radiotherapy (RT) with concomitant and adjuvant temozolomide (TMZ) chemotherapy is the current standard of care for patients with newly diagnosed GB up to age 70. Recently, a new standard of care has been adopted for elderly patients (\u2265 65 years) based on short course of RT and TMZ. Several clinically relevant molecular markers that assist in diagnosis and prognosis have recently been identified. The treatment for recurrent GB is not well defined, and decision-making is usually based on prior strategies as well as several clinical and radiological factors. The presence of neurologic deficits and seizures can significantly impact quality of life.","upload_link":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=29086250&authtype=shib&custid=ns346513&group=main&profile=eds","no_of_pages":"","authored_by":"Mart\u00ednez-Garcia M, \u00c1lvarez-Linera J, Carrato C, Ley L, Luque R, Maldonado X, Mart\u00ednez-Aguillo M, Navarro LM, Vaz-Salgado MA, Gil-Gil M","header":{"DbId":"mdl","DbLabel":"MEDLINE Ultimate","An":"29086250","RelevancyScore":"830","PubType":"Academic Journal","PubTypeId":"academicJournal","PreciseRelevancyScore":"830.118103027344"},"plink":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=29086250&authtype=shib&custid=ns346513&group=main&profile=eds","physicalDescription":{"Pagination":{"StartPage":"22"}},"additionalInfo":{"Authored_By":"Mart\u00ednez-Garcia M, \u00c1lvarez-Linera J, Carrato C, Ley L, Luque R, Maldonado X, Mart\u00ednez-Aguillo M, Navarro LM, Vaz-Salgado MA, Gil-Gil M","Journal_Info":"Publisher: Country of Publication: Italy NLM ID: 101247119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE","Publication_Type":"Journal Article; Practice Guideline","Published_Date":"2018-01-01","Source":"Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2018 Jan; Vol. 20 (1), pp. 22-28. Date of Electronic Publication: 2017 Oct 30.","Languages":"English","Electronic_ISSN":"1699-3055","MeSH_Terms":"Brain Neoplasms\/*diagnosis , Brain Neoplasms\/*therapy , Glioma\/*diagnosis , Glioma\/*therapy, Humans","Subjects":"Humans, Brain Neoplasms diagnosis, Brain Neoplasms therapy, Glioma diagnosis, Glioma therapy","Title_Abbreviations":"Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico","Volume":"20"}}