Management of oropharyngeal squamous cell carcinoma.

{"article_title":"Management of oropharyngeal squamous cell carcinoma.","author":"Gr\u00e9goire V, Giraud P, Vieillevigne L, Maingon P","journal_title":"Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique","issn":"1769-6658","isbn":"","publication_date":"2022-02-01","volume":"26","issue":"1-Feb","first_page":"174","page_count":"","accession_number":"34953693","doi":"10.1016\/j.canrad.2021.10.002","publisher":"Elsevier","doctype":"Journal Article","subjects":"France; Oropharyngeal Neoplasms radiotherapy; Squamous Cell Carcinoma of Head and Neck radiotherapy; Brachytherapy methods; Cyclin-Dependent Kinase Inhibitor p16 metabolism; Dose Fractionation, Radiation; France; Humans; Induction Chemotherapy methods; Neck Dissection; Neoplasm Recurrence, Local radiotherapy; Neoplasm Recurrence, Local surgery; Oropharyngeal Neoplasms diagnostic imaging; Oropharyngeal Neoplasms pathology; Oropharyngeal Neoplasms surgery; Radiation Oncology; Retreatment; Societies, Medical; Squamous Cell Carcinoma of Head and Neck diagnostic imaging; Squamous Cell Carcinoma of Head and Neck pathology; Squamous Cell Carcinoma of Head and Neck surgery","interest_area":["ENT"," Oncology"],"abstract":"This article reviews the various treatment options, by primary or postoperative external radiotherapy and by brachytherapy for the p16-negative oropharyngeal squamous cell carcinoma. Dose levels, fractionation and association with systemic treatments are presented. The need for neck node dissection post local treatment is discussed, as well as specificities for the management of p16-positive tumours. Guidelines for target volume selection and delineation are thoroughly elaborated. Last, the management by radiotherapy of locoregional recurrences is discussed. Copyright \u00a9 2021. Published by Elsevier Masson SAS.","url":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&db=mdl&AN=34953693","isPdfLink":false,"isSAML":false,"an":"34953693","number_other":"","type_pub":"","issn_electronic":"1769-6658","languages":"English","language":"eng","date_entry":"Date Created: 20211226 Date Completed: 20220217 Latest Revision: 20220217","date_update":"20240104","titleSource":"Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2022 Feb-Apr; Vol. 26 (1-2), pp. 174-188. Date of Electronic Publication: 2021 Dec 22.","date_pub_cy":"","type_document":"","contract_publisher":"","authored_on":"2022-02-01","description":"This article reviews the various treatment options, by primary or postoperative external radiotherapy and by brachytherapy for the p16-negative oropharyngeal squamous cell carcinoma. Dose levels, fractionation and association with systemic treatments are presented. The need for neck node dissection post local treatment is discussed, as well as specificities for the management of p16-positive tumours. Guidelines for target volume selection and delineation are thoroughly elaborated. Last, the management by radiotherapy of locoregional recurrences is discussed.<br \/> (Copyright © 2021. Published by Elsevier Masson SAS.)","upload_link":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&scope=site&db=mdl&AN=34953693&authtype=shib&custid=ns346513&group=main&profile=eds","no_of_pages":"","authored_by":"Gr\u00e9goire V, Giraud P, Vieillevigne L, Maingon P"}