{"article_title":"ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies.","author":"Grasselli G et al.","journal_title":"Intensive care medicine","issn":"1432-1238","isbn":"","publication_date":"2023 Jul","volume":"49","issue":"7","first_page":"727","page_count":"","accession_number":"37326646","doi":"10.1007\/s00134-023-07050-7","publisher":"Springer Verlag","doctype":"Journal Article","subjects":"COVID-19 therapy; Respiratory Distress Syndrome therapy; Adult; Humans; Respiration, Artificial; Positive-Pressure Respiration; Critical Care","interest_area":["Pulmonology"," Emergency Medicine"],"abstract":"The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to adult patients and to non-pharmacological respiratory support strategies across different aspects of acute respiratory distress syndrome (ARDS), including ARDS due to coronavirus disease 2019 (COVID-19). These guidelines were formulated by an international panel of clinical experts, one methodologist and patients' representatives on behalf of the ESICM. The review was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. We followed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence and grade recommendations and the quality of reporting of each study based on the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) network guidelines. The CPG addressed 21 questions and formulates 21 recommendations on the following domains: (1) definition; (2) phenotyping, and respiratory support strategies including (3) high-flow nasal cannula oxygen (HFNO); (4) non-invasive ventilation (NIV); (5) tidal volume setting; (6) positive end-expiratory pressure (PEEP) and recruitment maneuvers (RM); (7) prone positioning; (8) neuromuscular blockade, and (9) extracorporeal life support (ECLS). In addition, the CPG includes expert opinion on clinical practice and identifies the areas of future research. \u00a9 2023. The Author(s).","url":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&db=mdl&AN=37326646&authtype=shib&custid=ns346513","isPdfLink":true,"isSAML":false,"additionalInfo":{"Authored_By":"Grasselli G, Calfee CS, Camporota L, Poole D, Amato MBP, Antonelli M, Arabi YM, Baroncelli F, Beitler JR, Bellani G, Bellingan G, Blackwood B, Bos LDJ, Brochard L, Brodie D, Burns KEA, Combes A, D'Arrigo S, De Backer D, Demoule A, Einav S, Fan E, Ferguson ND, Frat JP, Gattinoni L, Gu\u00e9rin C, Herridge MS, Hodgson C, Hough CL, Jaber S, Juffermans NP, Karagiannidis C, Kesecioglu J, Kwizera A, Laffey JG, Mancebo J, Matthay MA, McAuley DF, Mercat A, Meyer NJ, Moss M, Munshi L, Myatra SN, Ng Gong M, Papazian L, Patel BK, Pellegrini M, Perner A, Pesenti A, Piquilloud L, Qiu H, Ranieri MV, Riviello E, Slutsky AS, Stapleton RD, Summers C, Thompson TB, Valente Barbas CS, Villar J, Ware LB, Weiss B, Zampieri FG, Azoulay E, Cecconi M","Corporate_Authors":"European Society of Intensive Care Medicine Taskforce on ARDS","Journal_Info":"Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1238 (Electronic) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE","Publication_Type":"Journal Article","Published_Date":"2023-07-01","Source":"Intensive care medicine [Intensive Care Med] 2023 Jul; Vol. 49 (7), pp. 727-759. Date of Electronic Publication: 2023 Jun 16.","Languages":"English","Electronic_ISSN":"1432-1238","MeSH_Terms":"COVID-19*\/therapy , Respiratory Distress Syndrome*\/therapy, Adult ; Humans ; Respiration, Artificial ; Positive-Pressure Respiration ; Critical Care","Subjects":"Adult, Humans, Respiration, Artificial, Positive-Pressure Respiration, Critical Care, COVID-19 therapy, Respiratory Distress Syndrome therapy","Title_Abbreviations":"Intensive care medicine","Volume":"49"},"header":{"DbId":"mdl","DbLabel":"MEDLINE Ultimate","An":"37326646","RelevancyScore":"913","PubType":"Academic Journal","PubTypeId":"academicJournal","PreciseRelevancyScore":"913.373657226563"},"plink":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=37326646&authtype=shib&custid=ns346513&group=main&profile=eds","upload_link":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=37326646&authtype=shib&custid=ns346513&group=main&profile=eds"}