Provider variability in the initial diagnosis and treatment of congenital hypothyroidism.
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Clinical Guidelines
Authored By
Cielonko L, Hamby T, Dallas JS, Hamilton L, Wilson DP
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Interests
Pediatric Medicine
Endocrinology
Speciality
Pediatric Medicine
Endocrinology
Book Detail
volume
30
ISSN
2191-0251
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["Cielonko L, Hamby T, Dallas JS, Hamilton L, Wilson DP","Publisher: Walter de Gruyter Country of Publication: Germany NLM ID: 9508900 Publication Model: Print Cited Medium: Internet ISSN: 2191-0251 (Electronic) Linking ISSN: 0334018X NLM ISO Abbreviation: J Pediatr Endocrinol Metab Subsets: MEDLINE","Journal Article","2017-05-01","Journal of pediatric endocrinology & metabolism : JPEM [J Pediatr Endocrinol Metab] 2017 May 01; Vol. 30 (5), pp. 583-586.","English","2191-0251","Congenital Hypothyroidism\/*diagnosis , Congenital Hypothyroidism\/*drug therapy , Guideline Adherence\/*trends , Neonatal Screening\/*standards , Practice Guidelines as Topic\/*standards , Practice Patterns, Physicians'\/*trends , Thyroxine\/*therapeutic use, Early Diagnosis ; Humans ; Infant, Newborn ; Intellectual Disability\/prevention & control ; Surveys and Questionnaires ; United Kingdom","Early Diagnosis, Humans, Infant, Newborn, Intellectual Disability prevention & control, Surveys and Questionnaires, United Kingdom, Congenital Hypothyroidism diagnosis, Congenital Hypothyroidism drug therapy, Guideline Adherence trends, Neonatal Screening standards, Practice Guidelines as Topic standards, Practice Patterns, Physicians' trends, Thyroxine therapeutic use","Journal of pediatric endocrinology & metabolism : JPEM","30"]
Description
Background: Early diagnosis and expeditious treatment of newborns with congenital hypothyroidism (CH) is necessary to avoid mental retardation.<br />Methods: A survey of 44 practitioners in the southern US was conducted to better understand common practices regarding neonatal CH and the findings were compared with current guidelines in the US and Europe.<br />Results: Responses indicated some consensus that 10-15 μg of thyroid hormone/kg/day was the appropriate dosage. However, despite guidelines advocating their use, practitioners reported that they did not commonly use imaging or laboratory tests, though experienced providers apparently used them more often.<br />Conclusions: Together, these results show moderate adherence to published guidelines for treating and diagnosing CH. Further research is needed to determine why providers deviate from these guidelines and to generalize these results to other populations.