An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients.

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Clinical Guidelines
Authored By
Levy N, Quinlan J, El-Boghdadly K, Fawcett WJ, Agarwal V, Bastable RB, Cox FJ, de Boer HD, Dowdy SC, Hattingh K, Knaggs RD, Mariano ER, Pelosi P, Scott MJ, Lobo DN, Macintyre PE
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Pain & Anesthesiology
Internal/Family Medicine
Speciality
Pain & Anesthesiology
Internal/Family Medicine
Book Detail
volume
76
ISSN
1365-2044
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An international panel of healthcare professionals evaluated the literature relating to postoperative opioid-related harm, including persistent postoperative opioid use; opioid-induced ventilatory impairment; non-medical opioid use; opioid diversion and dependence; and driving under the influence of prescription opioids. Recommended strategies to reduce harm include pre-operative assessment of the risk of persistent postoperative opioid use; use of an assessment of patient function rather than unidimensional pain scores alone to guide adequacy of analgesia; avoidance of long-acting (modified-release and transdermal patches) opioid formulations and combination analgesics; limiting the number of tablets prescribed at discharge; providing deprescribing advice; avoidance of automatic prescription refills; safe disposal of unused medicines; reducing the risk of opioid diversion; and better education of healthcare professionals, patients and carers. This consensus statement provides a framework for better prescribing practices that could help reduce the risk of postoperative opioid-related harm in adults. \u00a9 2020 Association of Anaesthetists.","url":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&db=mdl&AN=33027841","isPdfLink":true,"isSAML":false,"an":"33027841","number_other":"","type_pub":"","issn_electronic":"1365-2044","languages":"English","language":"eng","date_entry":"","date_update":"","titleSource":"Anaesthesia [Anaesthesia] 2021 Apr; Vol. 76 (4), pp. 520-536. Date of Electronic Publication: 2020 Oct 07.","date_pub_cy":"","type_document":"","contract_publisher":"","authored_on":"2021-04-01","description":"This international multidisciplinary consensus statement was developed to provide balanced guidance on the safe peri-operative use of opioids in adults. An international panel of healthcare professionals evaluated the literature relating to postoperative opioid-related harm, including persistent postoperative opioid use; opioid-induced ventilatory impairment; non-medical opioid use; opioid diversion and dependence; and driving under the influence of prescription opioids. Recommended strategies to reduce harm include pre-operative assessment of the risk of persistent postoperative opioid use; use of an assessment of patient function rather than unidimensional pain scores alone to guide adequacy of analgesia; avoidance of long-acting (modified-release and transdermal patches) opioid formulations and combination analgesics; limiting the number of tablets prescribed at discharge; providing deprescribing advice; avoidance of automatic prescription refills; safe disposal of unused medicines; reducing the risk of opioid diversion; and better education of healthcare professionals, patients and carers. This consensus statement provides a framework for better prescribing practices that could help reduce the risk of postoperative opioid-related harm in adults.<br \/> (© 2020 Association of Anaesthetists.)","upload_link":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=33027841&authtype=shib&custid=ns346513&group=main&profile=eds","no_of_pages":"","authored_by":"Levy N, Quinlan J, El-Boghdadly K, Fawcett WJ, Agarwal V, Bastable RB, Cox FJ, de Boer HD, Dowdy SC, Hattingh K, Knaggs RD, Mariano ER, Pelosi P, Scott MJ, Lobo DN, Macintyre PE","header":{"DbId":"mdl","DbLabel":"MEDLINE Ultimate","An":"33027841","RelevancyScore":"886","PubType":"Academic Journal","PubTypeId":"academicJournal","PreciseRelevancyScore":"885.627746582031"},"plink":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=33027841&authtype=shib&custid=ns346513&group=main&profile=eds","physicalDescription":{"Pagination":{"StartPage":"520"}},"additionalInfo":{"Authored_By":"Levy N, Quinlan J, El-Boghdadly K, Fawcett WJ, Agarwal V, Bastable RB, Cox FJ, de Boer HD, Dowdy SC, Hattingh K, Knaggs RD, Mariano ER, Pelosi P, Scott MJ, Lobo DN, Macintyre PE","Journal_Info":"Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0370524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2044 (Electronic) Linking ISSN: 00032409 NLM ISO Abbreviation: Anaesthesia Subsets: MEDLINE","Publication_Type":"Journal Article; Practice Guideline","Published_Date":"2021-04-01","Source":"Anaesthesia [Anaesthesia] 2021 Apr; Vol. 76 (4), pp. 520-536. Date of Electronic Publication: 2020 Oct 07.","Languages":"English","Electronic_ISSN":"1365-2044","MeSH_Terms":"Analgesics, Opioid\/*adverse effects , Opioid-Related Disorders\/*prevention & control, Analgesics, Opioid\/therapeutic use ; Humans ; Mental Disorders\/complications ; Opioid-Related Disorders\/etiology ; Pain, Postoperative\/complications ; Pain, Postoperative\/drug therapy ; Postoperative Care ; Prescription Drug Overuse ; Risk Factors","Subjects":"Analgesics, Opioid therapeutic use, Humans, Mental Disorders complications, Opioid-Related Disorders etiology, Pain, Postoperative complications, Pain, Postoperative drug therapy, Postoperative Care, Prescription Drug Overuse, Risk Factors, Analgesics, Opioid adverse effects, Opioid-Related Disorders prevention & control","Title_Abbreviations":"Anaesthesia","Volume":"76"}}
ISSN
1365-2044
IS_Ebsco
true
Additional Info
["Levy N, Quinlan J, El-Boghdadly K, Fawcett WJ, Agarwal V, Bastable RB, Cox FJ, de Boer HD, Dowdy SC, Hattingh K, Knaggs RD, Mariano ER, Pelosi P, Scott MJ, Lobo DN, Macintyre PE","Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0370524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2044 (Electronic) Linking ISSN: 00032409 NLM ISO Abbreviation: Anaesthesia Subsets: MEDLINE","Journal Article; Practice Guideline","2021-04-01","Anaesthesia [Anaesthesia] 2021 Apr; Vol. 76 (4), pp. 520-536. Date of Electronic Publication: 2020 Oct 07.","English","1365-2044","Analgesics, Opioid\/*adverse effects , Opioid-Related Disorders\/*prevention & control, Analgesics, Opioid\/therapeutic use ; Humans ; Mental Disorders\/complications ; Opioid-Related Disorders\/etiology ; Pain, Postoperative\/complications ; Pain, Postoperative\/drug therapy ; Postoperative Care ; Prescription Drug Overuse ; Risk Factors","Analgesics, Opioid therapeutic use, Humans, Mental Disorders complications, Opioid-Related Disorders etiology, Pain, Postoperative complications, Pain, Postoperative drug therapy, Postoperative Care, Prescription Drug Overuse, Risk Factors, Analgesics, Opioid adverse effects, Opioid-Related Disorders prevention & control","Anaesthesia","76"]
Description

This international multidisciplinary consensus statement was developed to provide balanced guidance on the safe peri-operative use of opioids in adults. An international panel of healthcare professionals evaluated the literature relating to postoperative opioid-related harm, including persistent postoperative opioid use; opioid-induced ventilatory impairment; non-medical opioid use; opioid diversion and dependence; and driving under the influence of prescription opioids. Recommended strategies to reduce harm include pre-operative assessment of the risk of persistent postoperative opioid use; use of an assessment of patient function rather than unidimensional pain scores alone to guide adequacy of analgesia; avoidance of long-acting (modified-release and transdermal patches) opioid formulations and combination analgesics; limiting the number of tablets prescribed at discharge; providing deprescribing advice; avoidance of automatic prescription refills; safe disposal of unused medicines; reducing the risk of opioid diversion; and better education of healthcare professionals, patients and carers. This consensus statement provides a framework for better prescribing practices that could help reduce the risk of postoperative opioid-related harm in adults.<br /> (© 2020 Association of Anaesthetists.)

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