EAACI guidelines: Anaphylaxis (2021 update).

Select Content Type
Clinical Guidelines
Authored By
Muraro A, Worm M, Alviani C, Cardona V, DunnGalvin A, Garvey LH, Riggioni C, de Silva D, Angier E, Arasi S, Bellou A, Beyer K, Bijlhout D, Bilò MB, Bindslev-Jensen C, Brockow K, Fernandez-Rivas M, Hal
Authored On
Interests
Immunology Allergy & Inflammation
Speciality
Immunology Allergy & Inflammation
Book Detail
volume
77
ISSN
1398-9995
Publication Date
Actions
Download in App
Promotional Categories
Featured
Event Data
{"article_title":"EAACI guidelines: Anaphylaxis (2021 update).","author":"Muraro A, Worm M, Alviani C, Cardona V, DunnGalvin A, Garvey LH, Riggioni C, de Silva D, Angier E, Arasi S, Bellou A, Beyer K, Bijlhout D, Bil\u00f2 MB, Bindslev-Jensen C, Brockow K, Fernandez-Rivas M, Halken S, Jensen B, Khaleva E, Michaelis LJ, Oude Elberink HNG, Regent L, Sanchez A, Vlieg-Boerstra BJ, Roberts G","journal_title":"Allergy","issn":"1398-9995","isbn":"","publication_date":"2022-02-01","volume":"77","issue":"2","first_page":"357","page_count":"","accession_number":"34343358","doi":"","publisher":"Wiley-Blackwell","doctype":"Journal Article","subjects":"Anaphylaxis diagnosis; Anaphylaxis etiology; Anaphylaxis therapy; Epinephrine therapeutic use; Humans; Tryptases","interest_area":["Allergy Immunology & Inflammation"],"abstract":"Anaphylaxis is a clinical emergency which all healthcare professionals need to be able to recognize and manage. The European Academy of Allergy and Clinical Immunology Anaphylaxis multidisciplinary Task Force has updated the 2014 guideline. The guideline was developed using the AGREE II framework and the GRADE approach. The evidence was systematically reviewed and recommendations were created by weighing up benefits and harms. The guideline was peer-reviewed by external experts and reviewed in a public consultation. The use of clinical criteria to identify anaphylaxis is suggested with blood sampling for the later measurement of tryptase. The prompt use of intramuscular adrenaline as first-line management is recommended with the availability of adrenaline autoinjectors to patients in the community. Pharmacokinetic data should be provided for adrenaline autoinjector devices. Structured, comprehensive training for people at risk of anaphylaxis is recommended. Simulation training and visual prompts for healthcare professionals are suggested to improve the management of anaphylaxis. It is suggested that school policies reflect anaphylaxis guidelines. The evidence for the management of anaphylaxis remains mostly at a very low level. There is an urgent need to prioritize clinical trials with the potential to improve the management of patients at risk of anaphylaxis. \u00a9 2021 EAACI and John Wiley and Sons A\/S. Published by John Wiley and Sons Ltd.","url":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&db=mdl&AN=34343358","isPdfLink":true,"isSAML":false,"an":"34343358","number_other":"","type_pub":"","issn_electronic":"1398-9995","languages":"English","language":"eng","date_entry":"","date_update":"","titleSource":"Allergy [Allergy] 2022 Feb; Vol. 77 (2), pp. 357-377. Date of Electronic Publication: 2021 Sep 01.","date_pub_cy":"","type_document":"","contract_publisher":"","authored_on":"2022-02-01","description":"Anaphylaxis is a clinical emergency which all healthcare professionals need to be able to recognize and manage. The European Academy of Allergy and Clinical Immunology Anaphylaxis multidisciplinary Task Force has updated the 2014 guideline. The guideline was developed using the AGREE II framework and the GRADE approach. The evidence was systematically reviewed and recommendations were created by weighing up benefits and harms. The guideline was peer-reviewed by external experts and reviewed in a public consultation. The use of clinical criteria to identify anaphylaxis is suggested with blood sampling for the later measurement of tryptase. The prompt use of intramuscular adrenaline as first-line management is recommended with the availability of adrenaline autoinjectors to patients in the community. Pharmacokinetic data should be provided for adrenaline autoinjector devices. Structured, comprehensive training for people at risk of anaphylaxis is recommended. Simulation training and visual prompts for healthcare professionals are suggested to improve the management of anaphylaxis. It is suggested that school policies reflect anaphylaxis guidelines. The evidence for the management of anaphylaxis remains mostly at a very low level. There is an urgent need to prioritize clinical trials with the potential to improve the management of patients at risk of anaphylaxis.<br \/> (© 2021 EAACI and John Wiley and Sons A\/S. Published by John Wiley and Sons Ltd.)","upload_link":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=34343358&authtype=shib&custid=ns346513&group=main&profile=eds","no_of_pages":"","authored_by":"Muraro A, Worm M, Alviani C, Cardona V, DunnGalvin A, Garvey LH, Riggioni C, de Silva D, Angier E, Arasi S, Bellou A, Beyer K, Bijlhout D, Bil\u00f2 MB, Bindslev-Jensen C, Brockow K, Fernandez-Rivas M, Halken S, Jensen B, Khaleva E, Michaelis LJ, Oude Elberink HNG, Regent L, Sanchez A, Vlieg-Boerstra BJ, Roberts G","header":{"DbId":"mdl","DbLabel":"MEDLINE Ultimate","An":"34343358","RelevancyScore":"915","PubType":"Academic Journal","PubTypeId":"academicJournal","PreciseRelevancyScore":"914.586853027344"},"plink":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&site=eds-live&db=mdl&AN=34343358&authtype=shib&custid=ns346513&group=main&profile=eds","physicalDescription":{"Pagination":{"StartPage":"357"}},"additionalInfo":{"Authored_By":"Muraro A, Worm M, Alviani C, Cardona V, DunnGalvin A, Garvey LH, Riggioni C, de Silva D, Angier E, Arasi S, Bellou A, Beyer K, Bijlhout D, Bil\u00f2 MB, Bindslev-Jensen C, Brockow K, Fernandez-Rivas M, Halken S, Jensen B, Khaleva E, Michaelis LJ, Oude Elberink HNG, Regent L, Sanchez A, Vlieg-Boerstra BJ, Roberts G","Corporate_Authors":"European Academy of Allergy and Clinical Immunology, Food Allergy, Anaphylaxis Guidelines Group","Journal_Info":"Publisher: Wiley-Blackwell Country of Publication: Denmark NLM ID: 7804028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1398-9995 (Electronic) Linking ISSN: 01054538 NLM ISO Abbreviation: Allergy Subsets: MEDLINE","Publication_Type":"Journal Article; Practice Guideline; Research Support, Non-U.S. Gov't","Published_Date":"2022-02-01","Source":"Allergy [Allergy] 2022 Feb; Vol. 77 (2), pp. 357-377. Date of Electronic Publication: 2021 Sep 01.","Languages":"English","Electronic_ISSN":"1398-9995","MeSH_Terms":"Anaphylaxis*\/diagnosis , Anaphylaxis*\/etiology , Anaphylaxis*\/therapy, Epinephrine\/therapeutic use ; Humans ; Tryptases","Subjects":"Epinephrine therapeutic use, Humans, Tryptases, Anaphylaxis diagnosis, Anaphylaxis etiology, Anaphylaxis therapy","Title_Abbreviations":"Allergy","Volume":"77"}}
ISSN
1398-9995
IS_Ebsco
true
Additional Info
["Muraro A, Worm M, Alviani C, Cardona V, DunnGalvin A, Garvey LH, Riggioni C, de Silva D, Angier E, Arasi S, Bellou A, Beyer K, Bijlhout D, Bil\u00f2 MB, Bindslev-Jensen C, Brockow K, Fernandez-Rivas M, Halken S, Jensen B, Khaleva E, Michaelis LJ, Oude Elberink HNG, Regent L, Sanchez A, Vlieg-Boerstra BJ, Roberts G","European Academy of Allergy and Clinical Immunology, Food Allergy, Anaphylaxis Guidelines Group","Publisher: Wiley-Blackwell Country of Publication: Denmark NLM ID: 7804028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1398-9995 (Electronic) Linking ISSN: 01054538 NLM ISO Abbreviation: Allergy Subsets: MEDLINE","Journal Article; Practice Guideline; Research Support, Non-U.S. Gov't","2022-02-01","Allergy [Allergy] 2022 Feb; Vol. 77 (2), pp. 357-377. Date of Electronic Publication: 2021 Sep 01.","English","1398-9995","Anaphylaxis*\/diagnosis , Anaphylaxis*\/etiology , Anaphylaxis*\/therapy, Epinephrine\/therapeutic use ; Humans ; Tryptases","Epinephrine therapeutic use, Humans, Tryptases, Anaphylaxis diagnosis, Anaphylaxis etiology, Anaphylaxis therapy","Allergy","77"]
Description
Anaphylaxis is a clinical emergency which all healthcare professionals need to be able to recognize and manage. The European Academy of Allergy and Clinical Immunology Anaphylaxis multidisciplinary Task Force has updated the 2014 guideline. The guideline was developed using the AGREE II framework and the GRADE approach. The evidence was systematically reviewed and recommendations were created by weighing up benefits and harms. The guideline was peer-reviewed by external experts and reviewed in a public consultation. The use of clinical criteria to identify anaphylaxis is suggested with blood sampling for the later measurement of tryptase. The prompt use of intramuscular adrenaline as first-line management is recommended with the availability of adrenaline autoinjectors to patients in the community. Pharmacokinetic data should be provided for adrenaline autoinjector devices. Structured, comprehensive training for people at risk of anaphylaxis is recommended. Simulation training and visual prompts for healthcare professionals are suggested to improve the management of anaphylaxis. It is suggested that school policies reflect anaphylaxis guidelines. The evidence for the management of anaphylaxis remains mostly at a very low level. There is an urgent need to prioritize clinical trials with the potential to improve the management of patients at risk of anaphylaxis.<br /> (© 2021 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.)
Published Date