Postexposure Prophylaxis and Treatment of Bacillus anthracis Infections: A Systematic Review and Meta-analyses of Animal Models, 1947-2019.

{"article_title":"Postexposure Prophylaxis and Treatment of Bacillus anthracis Infections: A Systematic Review and Meta-analyses of Animal Models, 1947-2019.","author":"Kennedy, Jordan L , Bulitta, Jurgen B , Chatham-Stephens, Kevin , Person, Marissa K , Cook, Rachel , Mongkolrattanothai, Thitipong , Shin, Eunjeong , Yu, Patricia , Negron, Maria E , Bower, William A , Hendricks, Katherine","journal_title":"Clinical infectious diseases : an official publication of the Infectious Diseases Society of America","issn":"1537-6591 ; Electronic","isbn":"","publication_date":"20221017","volume":"75","issue":"Suppl 3","first_page":"S379","page_count":"","accession_number":"36251546","doi":"10.1093\/cid\/ciac591","publisher":"Oxford University Press","doctype":"Journal Article; Meta-Analysis; Systematic Review","subjects":"Pharmacology ","interest_area":["Infectious Disease & Vaccines"],"abstract":"Anthrax is endemic to many countries, including the United States. The causative agent, Bacillus anthracis, poses a global bioterrorism threat. Without effective antimicrobial postexposure prophylaxis (PEPAbx) and treatment, the mortality of systemic anthrax is high. To inform clinical guidelines for PEPAbx and treatment of B. anthracis infections in humans, we systematically evaluated animal anthrax treatment model studies.","url":"https:\/\/search.ebscohost.com\/login.aspx?direct=true&db=mdl&AN=36251546&authtype=shib&custid=ns346513"}